Invention Grant
- Patent Title: Methods and compositions involving lincRNA and leukemia
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Application No.: US14776458Application Date: 2014-03-14
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Publication No.: US09909188B2Publication Date: 2018-03-06
- Inventor: Dinesh S. Rao , Ella Waters , Norma I. Rodriguez-Malave , Thilini Fernando
- Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Norton Rose Fulbright US LLP
- International Application: PCT/US2014/027313 WO 20140314
- International Announcement: WO2014/152411 WO 20140925
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12N15/113 ; A61K31/573 ; G01N33/50
Abstract:
The instant disclosure relates to the finding that lincRNA expression is associated with particular cytogenetic abnormalities and is related to disease pathogenesis of certain cancers. Long intergenic non-coding RNAs (lincRNAs) have been found to play a role in gene regulation, but their expression has not been described in B acute lymphoblastic leukemia (B-ALL). Methods and compositions are provided regarding B-ALL associated long intergenic RNAs (BALIRs).
Public/Granted literature
- US20160145692A1 METHODS AND COMPOSITIONS INVOLVING LINCRNA AND LEUKEMIA Public/Granted day:2016-05-26
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