Pick hole guards are provided for use in guarding pick holes on manhole covers. In some embodiments of the present disclosure, the pick hole guards can have a base, biasing member, and guard member. The biasing member can be attached to the base and guard member, and can bias the guard member toward a pick hole on the manhole cover to guard the pick hole. In other embodiments, the pick hole guards do not have movable guard members, but instead have retaining surfaces to serve as a receptacle for catching waste disposed through a pick hole.