A control system for a combustor system including a plurality of can combustors, each can combustor accommodating combustion of a plurality of combustion fluids in a combustion chamber thereof is provided. The control system may include a calculator calculating: a) a pressure drop for each respective can combustor of the plurality of can combustors between a selected combustion fluid upstream of the combustion chamber and a combustion flow within the combustion chamber of the respective can combustor, and b) a differential between the respective pressure drop for each of the plurality of can combustors and an average pressure drop across all of the plurality of can combustors. The differentials identify can-to-can variation. A controller can modify a combustion parameter of at least one can combustor to reduce the differential for the at least one can combustor. The system can work iteratively to reduce can-to-can variation.