A refrigerator and/or freezer unit and system for storing, monitoring, and maintaining a supply of temperature sensitive pharmaceutical products in compliance with regulatory requirements. The unit contains compartments for each product type in multiple controlled temperature zones with sensors and readers to track product status and content. A user interface device in communication with an application service provider provides the user with a secure access to the content of the unit and product information. The application service provider provides the user with web accessed optimal management of product inventory.