Invention Grant
- Patent Title: Compositions and methods for modulating c-Rel-dependent cytokine production
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Application No.: US14542453Application Date: 2014-11-14
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Publication No.: US09910031B2Publication Date: 2018-03-06
- Inventor: Rongzhen Lu , James Barsoum , Yumiko Wada
- Applicant: Synta Pharmaceuticals Corporation
- Applicant Address: US PA West Conshohocken
- Assignee: Madrigal Pharmaceuticals, Inc.
- Current Assignee: Madrigal Pharmaceuticals, Inc.
- Current Assignee Address: US PA West Conshohocken
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- Agent Muriel Liberto, Esq.
- Main IPC: G01N33/50
- IPC: G01N33/50 ; G01N33/68
Abstract:
The present invention is directed to compositions and methods for modulating c-Rel-dependent cytokine production without materially altering the level of expression of NFκB and/or the amount of IκB. The present invention is also directed to screening for modulators of c-Rel activity as determined by assaying for altered subcellular localization of c-Rel but where the level of expression of NFκB and/or the amount of IκB is materially unaltered.
Public/Granted literature
- US20160003804A1 COMPOSITIONS AND METHODS FOR MODULATING C-REL-DEPENDENT CYTOKINE PRODUCTION Public/Granted day:2016-01-07
Information query
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