A vehicle mobile terminal manipulation system that manipulates a mobile terminal brought in a vehicle includes: a mobile terminal; a manipulation device to which a user inputs manipulation; and a notification portion that notifies the mobile terminal of manipulation information indicative of manipulation which has been input to the manipulation device. The mobile terminal includes a terminal-side display portion and a terminal-side manipulation portion. The mobile terminal has a user interface displayed on the terminal-side display portion at a time when independently operating according to manipulation conducted on the terminal-side manipulation portion. The mobile terminal causes the terminal-side display portion to display a user interface different from a case where the mobile terminal independently operates, when operating according to manipulation conducted on the manipulation device different in manipulation mode from the terminal-side manipulation portion of the mobile terminal.