A network node in a wireless communication network communicates an enhanced Physical Downlink Control Channel (ePDCCH) to a user equipment (UE). This begins with the transmission, to the UE, of a configuration message that indicates the mappings of eDPCCH onto resource elements for both a first eDPCCH set and a second eDPCCH set. The mapping for the first eDPCCH set avoids the use of resource elements already in use by a first type of signal (e.g., a Cell-Specific Reference Signal or CRS), whereas the mapping for the second eDPCCH set avoids the use of resource elements in use by a second type of signal. The choice of an eDPCCH set for transmitting data to a UE may then be dynamically made in order to avoid interference caused by the first or second types of signal.