Invention Grant
- Patent Title: Methods of preserving and protecting pancreatic beta cells and treating or preventing diabetes by inhibiting NOX-1
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Application No.: US15475518Application Date: 2017-03-31
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Publication No.: US09914910B2Publication Date: 2018-03-13
- Inventor: David Taylor-Fishwick
- Applicant: Eastern Virginia Medical School
- Applicant Address: US VA Norfolk
- Assignee: Eastern Virginia Medical School
- Current Assignee: Eastern Virginia Medical School
- Current Assignee Address: US VA Norfolk
- Agency: Wilmer Cutler Pickering Hale and Dorr LLP
- Main IPC: A01N43/42
- IPC: A01N43/42 ; A61K31/44 ; C12N5/071 ; A61K31/437 ; A61K31/444 ; A01N1/02 ; A61K31/5415 ; A61K31/713 ; A61K45/06 ; C07D279/20 ; C07D471/04 ; C12N15/113

Abstract:
Methods of preserving and/or protecting pancreatic beta cells by inhibiting NOX-1. In a further aspect, NOX-1 inhibitors are administered to a subject in order to preserve and/or protect beta cells in the prevention or treatment of diabetes. NOX-1 inhibitors are also disclosed.
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