Clothes dryer wireless moisture data transfer systems and energy-efficient methods of operation thereof are provided. One example method of operating a near field communication (NFC) tag includes determining whether a rotatable drum of a clothes dryer appliance is currently rotating. The NFC tag is secured to the drum. The method includes operating the NFC tag in an ultra-low power mode when it is determined that the drum is not currently rotating. The method includes periodically switching the NFC tag between a normal mode and a low power mode when it is determined that the drum is currently rotating.