A data storage system is provided that is configured to achieve end-to-end data protection. The system includes a server running a storage archive manager with a first fixity support module, and the system includes a tape drive running a second fixity support module. During operations, the storage archive manager reads a data file with associated fixity information from a disk storage device, and the storage archive manager builds a set of blocks from the data file for writing to the tape drive. The first fixity support module checks fixity of the set of blocks by processing the fixity information associated with the data file. The processing of the fixity information includes determining whether data in the set of blocks is out of order relative to data in the data file or whether data in the set of blocks is corrupt relative to the data in the data file.