The embodiment of the invention provides a method and an apparatus for calibrating a liquid crystal display device. The liquid crystal display device comprises a pixel array, each pixel of the pixel array comprises electrodes in inclined arrangement, wherein an inclined orientation of the electrodes in pixels of odd rows is different with an inclined orientation of the electrodes in pixels of even rows; the method comprises: measuring brightness of the pixels of odd rows in a plurality of gray scales and brightness of the pixels of even rows in the plurality of gray scales respectively in a predetermined direction; and adjusting data line voltages of the pixels of odd rows and/or data line voltages of the pixels of even rows, such that in the predetermined direction, in each one of the plurality of gray scales, brightness of the pixels of odd rows is equal to brightness of the pixels of even rows.