A surgical clip applier includes an actuation mechanism, a body portion, a jaw blade, and a clip cartridge, the jaw blade and clip cartridge removeably disposed within the body portion. The jaw blade including first and second opposed jaws operably connected to the actuation mechanism to effectuate closure of a surgical clip, the first and second opposed jaws connected to each other at a proximal end by a shank section. The clip cartridge disposed within the body portion adjacent to the jaw blade and configured to store at least one surgical clip therein. The clip cartridge having a first nub which abuts a first end of the shank section of the jaw blade, and a second nub which abuts a second end of the shank section of the jaw blade, such that longitudinal and vertical movement of the jaw blade is arrested.