Invention Grant
- Patent Title: Glycosylation method
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Application No.: US14655128Application Date: 2014-01-17
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Publication No.: US09931392B2Publication Date: 2018-04-03
- Inventor: Brendan Wren , Jon Cuccui , Sherif Abouelhadid
- Applicant: London School of Hygiene and Tropical Medicine
- Applicant Address: GB London
- Assignee: London School of Hygiene and Tropical Medicine
- Current Assignee: London School of Hygiene and Tropical Medicine
- Current Assignee Address: GB London
- Agency: Klarquist Sparkman, LLP
- Priority: GB1300956.8 20130118; GB1301023.6 20130121; GB1309068.3 20130520
- International Application: PCT/GB2014/050133 WO 20140117
- International Announcement: WO2014/111724 WO 20140724
- Main IPC: C12N9/10
- IPC: C12N9/10 ; C12P21/00 ; A61K39/02 ; C12N15/70 ; C12N15/74 ; C12N1/20 ; A61K39/09
Abstract:
The invention relates to microbial host cells engineered to produce glycoconjugate vaccines by stable integration of an acceptor protein and an oligosaccharyltransferase into the host's genome, wherein expression of the oligosaccharyltransferase is regulated.
Public/Granted literature
- US20150344928A1 GLYCOSYLATION METHOD Public/Granted day:2015-12-03
Information query
