Invention Grant
- Patent Title: Non-aqueous patch
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Application No.: US15646744Application Date: 2017-07-11
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Publication No.: US09931403B2Publication Date: 2018-04-03
- Inventor: Tatsuya Mori , Naoyuki Saida
- Applicant: Itochu Chemical Frontier Corporation , Oishi Koseido Co., Ltd.
- Applicant Address: JP Tokyo JP Saga
- Assignee: Itochu Chemical Frontier Corporation,Oishi Koseido Co., Ltd.
- Current Assignee: Itochu Chemical Frontier Corporation,Oishi Koseido Co., Ltd.
- Current Assignee Address: JP Tokyo JP Saga
- Agent G. Kenneth Smith
- Main IPC: A61K47/12
- IPC: A61K47/12 ; A61K9/70 ; A61K31/167

Abstract:
Non-aqueous patches comprising lidocaine, which is not dissolved and is present in a crystalline state, have poor permeability to the skin. Therefore, non-aqueous patches have a high concentration of lidocaine. It is pointed out that lidocaine has an adverse effect on the heart. Prolonged use of a high concentration of lidocaine causes side effects, such as shock, rubor, and irritating sensation. External preparations comprising more than 5 mass % of lidocaine are designated as powerful drugs, and cannot be used as household (nonprescription) medicine. Provided is a non-aqueous patch that is effective to relieve muscle pain, the non-aqueous patch comprising lidocaine and/or its reactant, and a dissolving agent composed of an organic acid and a polyalcohol, which are contained in a base.
Public/Granted literature
- US20170304449A1 NON-AQUEOUS PATCH Public/Granted day:2017-10-26
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