Invention Grant
- Patent Title: Methods and compositions for liposomal formulation of antigens and uses thereof
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Application No.: US15181028Application Date: 2016-06-13
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Publication No.: US09931419B2Publication Date: 2018-04-03
- Inventor: Gary Fujii , Francis C. Szoka, Jr. , Douglas S. Watson
- Applicant: MOLECULAR EXPRESS, INC. , THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Applicant Address: US CA Rancho Dominquez US CA Oakland
- Assignee: MOLECULAR EXPRESS, INC.,THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Current Assignee: MOLECULAR EXPRESS, INC.,THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Current Assignee Address: US CA Rancho Dominquez US CA Oakland
- Agency: Acuity Law Group, PC
- Agent Michael A. Whittaker
- Main IPC: A61K9/127
- IPC: A61K9/127 ; C12N7/00 ; A61K47/48 ; A61K39/145 ; A61K39/385 ; C07J9/00 ; C07J41/00 ; C07J43/00 ; A61K39/07 ; A61K39/12 ; A61K47/54 ; A61K47/69 ; A61K39/00
Abstract:
The present invention relates to liposomal vaccine compositions, methods for the manufacture thereof, and methods for the use thereof to stimulate an immune response in an animal. These compositions comprise dimyristoylphosphatidylcholine (“DMPC”); either dimyristoylphosphatidylglycerol (“DMPG”) or dimyristoyltrimethylammonium propane (“DMTAP”) or both DMPC and DMTAP; and at least one sterol derivative providing a covalent anchor for one or more immunogenic polypeptide(s) or carbohydrate(s).
Public/Granted literature
- US20170157266A1 METHODS AND COMPOSITIONS FOR LIPOSOMAL FORMULATION OF ANTIGENS AND USES THEREOF Public/Granted day:2017-06-08
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