Invention Grant
- Patent Title: Antimycotic polymerisable bone cement and a method for the production thereof
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Application No.: US15016534Application Date: 2016-02-05
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Publication No.: US09931430B2Publication Date: 2018-04-03
- Inventor: Sebastian Vogt
- Applicant: Heraeus Medical Gmbh
- Applicant Address: DE Wehrheim
- Assignee: HERAEUS MEDICAL GMBH
- Current Assignee: HERAEUS MEDICAL GMBH
- Current Assignee Address: DE Wehrheim
- Agency: Norris McLaughlin & Marcus PA
- Priority: DE102015102210 20150216
- Main IPC: A61L24/06
- IPC: A61L24/06 ; A61L24/04 ; A61L27/54 ; A61L24/00 ; A61K31/7048

Abstract:
The invention describes a bone cement with antimycotic efficacy based on organic polymers, such as polymethylmethacrylate. The bone cement comprises an antimycotic agent, in particular amphotericin B, that is released from the polymerized bone cement in the presence of water or aqueous media, such as body fluids. According to one alternative, the antimycotic agent is present in particulate form and is encapsulated, at least in part, by a mixture of at least one 1-methylamino-1-deoxy sugar alcohol and at least one fatty acid. In addition, a method for the production of a mixture comprising an antimycotic agent, such as amphotericin B particles, and 1-methylamino-1-deoxy sugar alcohol and at least one fatty acid is proposed. Preferably, the antimycotic agent is encapsulated, at least partially, by 1-methylamino-1-deoxy sugar alcohol and at least one fatty acid.
Public/Granted literature
- US20160235883A1 Antimycotic Polymerisable Bone Cement and a Method for the Production Thereof Public/Granted day:2016-08-18
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