A programming device receives a number of local coordinate systems from a user. Each local coordinate system is referenced directly or via at least one other local coordinate system to a global machine coordinate system of a motion-controlled machine. The programming device receives from the user, in each case with reference to one of the local coordinate systems, a number of positions to be approached by the end effector and/or a number of obstacles to be bypassed by the end effector. The programming device determines, with reference to the positions to be approached received from the user and the obstacles received from the user in the global machine coordinate system, the path to be traveled by the end effector The programming device stores the path to be traveled by the end effector as a first file so that it can be retrieved again at a later time.