Invention Grant
- Patent Title: N,N′-diarylurea compounds and N,N′-diarylthiourea compounds as inhibitors of translation initiation
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Application No.: US15216057Application Date: 2016-07-21
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Publication No.: US09932300B2Publication Date: 2018-04-03
- Inventor: Bertal Huseyin Aktas , José A. Halperin , Michael Chorev
- Applicant: President and Fellows of Harvard College
- Applicant Address: US MA Cambridge
- Assignee: President and Fellows of Harvard College
- Current Assignee: President and Fellows of Harvard College
- Current Assignee Address: US MA Cambridge
- Agency: Banner & Witcoff, Ltd.
- Main IPC: A61K31/519
- IPC: A61K31/519 ; C07C275/30 ; A61K31/5377 ; C07D213/75 ; C07D249/14 ; C07C275/34 ; C07C275/38 ; C07C275/40 ; C07D213/81 ; C07D215/06 ; C07D231/56 ; C07D233/36 ; C07D237/30 ; C07D239/34 ; C07D239/42 ; C07D261/14 ; C07D271/12 ; C07D277/18 ; C07D277/66 ; C07D285/14 ; C07D295/088 ; C07D295/135 ; C07D295/192 ; C07D307/88 ; C07D317/66 ; C07D319/08 ; C07D333/20 ; C07D333/38 ; C07D405/12 ; C07D409/04
Abstract:
Compositions and methods for inhibiting translation initiation are provided. Compositions, methods and kits for treating (1) cellular proliferative disorders, (2) non-proliferative, degenerative disorders, (3) viral infections, and/or (4) disorders associated with viral infections, using N,N′-diarylureas and/or N,N′-diarylthiourea compounds are described.
Public/Granted literature
- US20160318857A1 N,N'-Diarylurea Compounds and N,N'-Diarylthiourea Compounds as Inhibitors of Translation Initiation Public/Granted day:2016-11-03
Information query
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