Invention Grant
- Patent Title: Quinazoline compounds and their use in therapy
-
Application No.: US14385268Application Date: 2013-03-19
-
Publication No.: US09932317B2Publication Date: 2018-04-03
- Inventor: Robert Brown , Matthew John Fuchter , Nadine Chapman-Rothe , Nitipol Srimongkolpithak , Joachim Caron , James Snyder , Thota Ganesh , Jin Liu , Aiming Sun
- Applicant: Imperial Innovations Limited , Emory University
- Applicant Address: GB London US GA Atlanta
- Assignee: Imperial Innovations Limited,Emory University
- Current Assignee: Imperial Innovations Limited,Emory University
- Current Assignee Address: GB London US GA Atlanta
- Agency: Kilyk & Bowersox, P.L.L.C.
- International Application: PCT/GB2013/050689 WO 20130319
- International Announcement: WO2013/140148 WO 20130926
- Main IPC: C07D401/12
- IPC: C07D401/12 ; C07D401/14 ; A61K31/517 ; C07D239/95 ; C07D405/14 ; C07D491/056 ; C07D403/12 ; C07D401/04 ; A61K31/519 ; A61K31/5377 ; A61K31/55 ; A61K31/551
Abstract:
This invention relates to quinazoline compounds of Formula (I) which are inhibitors of the histone lysine methyltransferase (HKMTase) EZH2, and to uses of such compounds as medicaments, in particular in the treatment of a disease or disorder in which inhibition of EZH2 provides a therapeutic or prophylactic effect.
Public/Granted literature
- US20150057263A1 Quinazoline Compounds And Their Use In Therapy Public/Granted day:2015-02-26
Information query
