Invention Grant
- Patent Title: Inhibitors of IRAK4 activity
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Application No.: US15515377Application Date: 2015-09-25
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Publication No.: US09932350B2Publication Date: 2018-04-03
- Inventor: Michael D. Altman , Jason D. Brubaker , Matthew L. Childers , Anthony Donofrio , Thierry Fischmann , Craig R. Gibeau , Solomon D. Kattar , Charles A. Lesburg , Jongwon Lim , John K. F. Maclean , Umar F. Mansoor , Alan B. Northrup , John M. Sanders , Graham F. Smith
- Applicant: MERCK SHARP & DOHME CORP. , Craig R. Gibeau , Solomon D. Kattar , Charles A. Lesburg , Jongwon Lim , John K. F. Maclean , Umar F. Mansoor , Alan B. Northrup , John M. Sanders , Graham F. Smith
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Gloria M. Fuentes; Matthew A. Leff
- International Application: PCT/US2015/052116 WO 20150925
- International Announcement: WO2016/053772 WO 20160407
- Main IPC: C07D491/08
- IPC: C07D491/08 ; C07D239/94 ; A61K31/517 ; A61K45/06 ; C07D239/88 ; A61K31/5377 ; C07D403/12 ; C07D401/12 ; C07D413/12 ; A61K31/538 ; C07D491/052 ; A61K31/5386 ; C07D491/048 ; A61K31/55 ; C07D405/12

Abstract:
The present invention relates to inhibitors of IRAK4 of Formula I and provides compositions comprising such inhibitors, as well as methods therewith for treating IRAK4-mediated or -associated conditions or diseases.
Public/Granted literature
- US20170217981A1 INHIBITORS OF IRAK4 ACTIVITY Public/Granted day:2017-08-03
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