Invention Grant
- Patent Title: Chromatographic process for producing high purity fibrinogen and thrombin
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Application No.: US14883574Application Date: 2015-10-14
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Publication No.: US09932388B2Publication Date: 2018-04-03
- Inventor: Ashok Kumar Nuvula , Mitali Samaddar , Neelima Vadde , Zinia Chakraborty , Swapna Sagar Duggineni , Uma Devi Komath
- Applicant: HEMARUS THERAPEUTICS LIMITED
- Applicant Address: IN Hyderabad
- Assignee: Hemarus Therapeutics Limited
- Current Assignee: Hemarus Therapeutics Limited
- Current Assignee Address: IN Hyderabad
- Agent Harita S. Achanta
- Priority: IN5704/CHE/2014 20141113
- Main IPC: C07K14/75
- IPC: C07K14/75 ; A61L24/10 ; A61L24/02 ; C12N9/74
Abstract:
The present invention relates to a chromatographic process for obtaining purified fibrinogen and thrombin from human plasma. The purified fibrinogen and thrombin preparations contain plasminogen in amounts less than 1 ug/mL. The low levels of plasminogen eliminates use of a proteolytic inhibitor, such as aprotinin in fibrin sealant kits which are used for human therapeutic applications.
Public/Granted literature
- US20160137719A1 PROCESS FOR PRODUCING HIGH PURITY FIBRINOGEN AND THROMBIN FOR FIBRIN SEALANT Public/Granted day:2016-05-19
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