Invention Grant
- Patent Title: Differentiating induced pluripotent stem cells into glucose-responsive, insulin-secreting progeny
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Application No.: US14340161Application Date: 2014-07-24
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Publication No.: US09932561B2Publication Date: 2018-04-03
- Inventor: Tayaramma Thatava , Andre Terzic , Yogish C. Kudva , Yasuhiro Ikeda
- Applicant: Mayo Foundation for Medical Education and Research
- Applicant Address: US MN Rochester
- Assignee: Mayo Foundation for Medical Education and Research
- Current Assignee: Mayo Foundation for Medical Education and Research
- Current Assignee Address: US MN Rochester
- Agency: Fish & Richardson P.C.
- Main IPC: C12N5/071
- IPC: C12N5/071 ; C12N5/074
Abstract:
This document provides methods and materials related to differentiating iPS cells into glucose-responsive, insulin-secreting progeny. For example, methods and material for using indolactam V (ILV) and glucagon like peptide-1 (GLP-1) to produce glucose-responsive, insulin-secreting progeny from iPS cells are provided.
Public/Granted literature
- US20140356951A1 DIFFERENTIATING INDUCED PLURIPOTENT STEM CELLS INTO GLUCOSE-RESPONSIVE, INSULIN-SECRETING PROGENY Public/Granted day:2014-12-04
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