An exhaust gas purifying device includes a honeycomb catalyst body, a plugged honeycomb structure and a can member to receive therein the honeycomb catalyst body and the plugged honeycomb structure, and the plugged honeycomb structure disposed at a position on a downstream side of the honeycomb catalyst body is designed so that a pressure loss in an end face central region of at least one of a second inflow side end face and a second outflow side end face of a second honeycomb substrate is larger than a pressure loss of an end face circumferential region positioned around the end face central region.