Execution of an application is suspended and the runtime state of the application is collected and persisted. Execution of the application may be resumed based on the runtime state. A proxy layer might also be utilized to translate requests received from the application for resources that are modified after the runtime state of the application is persisted. For instance, the runtime state that is persisted may include first data identifying a resource in use by the application at the time the execution of the application is suspended. After resuming the execution of the application, the proxy layer may translate the first data included in a request for the resource to second data identifying the resource, or a different resource, at a time the execution of the application is resumed, and the second data can be used to provide the application access to the resource.