An AMOLED pixel driving circuit has a 5T1C structure, which includes a first, a second, a third, a fourth, and a fifth thin film transistors, a capacitor, and an organic light emitting diode (OLED). The first thin film transistor is a drive thin film transistor. A first global signal, a second global signal, and a scan signal are fed, with various combinations thereof, for various operations of the circuit in an initialization stage, a data writing stage, a threshold voltage compensation stage, and a drive stage. The data writing stage and the threshold voltage compensation stage are carried out simultaneously for effectively compensating threshold voltage variation of the drive thin film transistor and the organic light emitting diode to make the display brightness of the AMOLED uniform and to promote the display quality.