The present invention provides a panel signal control circuit, a display panel and a display device. The panel signal control circuit comprises: a PWM IC and a level shift IC, and the panel signal control circuit comprises further comprises: a Vin voltage divider circuit; one end of the Vin voltage divider circuit is coupled to an input port of an input working voltage Vin of the PWM IC, and the other end of the Vin voltage divider circuit is grounded; a voltage divider interface of the Vin voltage divider circuit is coupled to a pin a of the Level shift IC, and the pin a is a voltage monitor pin, and as the voltage of the pin a is lower than an activation voltage threshold, respective output clock CK pins of the Level shift IC output sync signals of an output working voltage VGH of the PWM IC.