An X-ray detection panel for X-ray detectors and a method of manufacturing the same are disclosed. The X-ray detection panel includes a substrate, a photodiode disposed on the substrate and generating an electrical signal in response to light illuminating the photodiode, a first thin-film transistor disposed on the substrate and processing the electrical signal generated by the photodiode, and a second thin-film transistor disposed on the substrate and removing a residual current component accumulated in the photodiode and the first thin-film transistor. The X-ray detection panel can improve actual sensitivity and signal-to-noise ratio (SNR).