The present invention relates to systems and methods for last mile optimization for the transmission of real-time data. Pseudo-packets are sent to a last mile optimizer located at each of several ‘best’ servers. The last mile optimizers provide feedback regarding jitter, latency and packet loss of the pseudo-packets to determine quality of service for each of the servers. The server with the best quality of service is selected as the ‘single best’ server. A plurality of transporter algorithms may then be applied to pseudo-packets that are then sent to the single best server, and the quality of service for each transporter algorithm is subsequently measured for effectiveness. The transporter algorithms that are shown to be effective are combined together for the actual transmission of real-time data. Continuous monitoring of transmission quality allows for utilizing backup pathways upon detection of a problem, and negotiation of preferred transporter algorithms.