Invention Grant
- Patent Title: C-ring modified tricyclic benzonaphthiridinone protein kinase inhibitors and use thereof
-
Application No.: US13140090Application Date: 2009-12-02
-
Publication No.: US09938268B2Publication Date: 2018-04-10
- Inventor: Yufang Xiao , Bayard R. Huck , Amanda E. Sutton , Thomas E. Richardson , Srinivasa R. Karra
- Applicant: Yufang Xiao , Bayard R. Huck , Amanda E. Sutton , Thomas E. Richardson , Srinivasa R. Karra
- Applicant Address: DE Darmstadt
- Assignee: Merck Patent GmbH
- Current Assignee: Merck Patent GmbH
- Current Assignee Address: DE Darmstadt
- Agency: EMD Serono Research and Development Institute
- Agent Thomas W. Brown
- International Application: PCT/US2009/066319 WO 20091202
- International Announcement: WO2010/077530 WO 20100708
- Main IPC: C07D471/04
- IPC: C07D471/04 ; C07D471/14 ; C07D491/147 ; C07D495/14
Abstract:
Disclosed are C-ring modified tricyclic benzonaphthiridinone compounds and analogs thereof, pharmaceutical compositions comprising such compounds and processes for preparing the same. The compounds are useful in the treatment of diseases amenable to protein kinase signal transduction inhibition, regulation and/or modulation.
Public/Granted literature
- US20110312951A1 C-Ring Modified Tricyclic Benzonaphthiridinone Protein Kinase Inhibitors and Use Thereof Public/Granted day:2011-12-22
Information query
