Invention Grant
- Patent Title: Purine inhibitors of human phosphatidylinositol 3-kinase delta
-
Application No.: US14443314Application Date: 2013-11-15
-
Publication No.: US09938281B2Publication Date: 2018-04-10
- Inventor: Abdelghani Abe Achab , Michael D. Altman , Yongqi Deng , Solomon Kattar , Jason D. Katz , Joey L. Methot , Hua Zhou , Meredeth McGowan , Matthew P. Christopher , Yudith Garcia , Neville John Anthony , Francesc Xavier Fradera Llinas , Liping Yang , Changwei Mu , Xiaona Wang , Feng Shi , Baijun Ye , Sixing Zhang , Xiaoli Zhao , Rong Zhang , Kin Chiu Fong , Xiansheng Leng
- Applicant: Merck Sharp & Dohme Corp.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Patricia A. Shatynski; John C. Todaro
- International Application: PCT/CN2013/001395 WO 20131115
- International Announcement: WO2014/075393 WO 20140522
- Main IPC: A61K31/52
- IPC: A61K31/52 ; A61K31/535 ; C07D473/00 ; C07D403/00 ; C07D487/04 ; C07D473/34 ; A61K45/06 ; A61K31/5377 ; A61K31/55 ; C07D519/00
Abstract:
The instant invention provides compounds of formula I which are PI3K-delta inhibitors, and as such are useful for the treatment of PI3K-delta-mediated diseases such as inflammation, asthma, COPD and cancer.
Public/Granted literature
- US20160207926A1 PURINE INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA Public/Granted day:2016-07-21
Information query
IPC分类:
