Invention Grant
- Patent Title: Humanized monoclonal antibodies and methods of use for the diagnosis and treatment of colon and pancreas cancer
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Application No.: US14655982Application Date: 2013-12-30
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Publication No.: US09938344B2Publication Date: 2018-04-10
- Inventor: Xue-Ping Wang , Philip M. Arlen
- Applicant: PRECISION BIOLOGICS, INC.
- Applicant Address: US MD Rockville
- Assignee: PRECISION BIOLOGICS, INC.
- Current Assignee: PRECISION BIOLOGICS, INC.
- Current Assignee Address: US MD Rockville
- Agency: LeClairRyan, A Professional Corporation
- Agent Robin L. Teskin
- International Application: PCT/US2013/078290 WO 20131230
- International Announcement: WO2014/106176 WO 20140703
- Main IPC: C07K16/28
- IPC: C07K16/28 ; G01N33/574 ; A61K39/395 ; A61K45/06 ; A61K39/00

Abstract:
This invention relates to humanized antibodies that selectively bind the 31.1 epitope on the A33 protein differentially expressed in cancers including, lung cancer, ovarian cancer, pancreas cancer, breast cancer, and colon cancer, and diagnostic and therapeutic usages.
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