Invention Grant
- Patent Title: Tissue-specific extracellular matrix with or without tissue protein components for cell culture
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Application No.: US13882429Application Date: 2011-11-04
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Publication No.: US09938502B2Publication Date: 2018-04-10
- Inventor: Yuanyuan Zhang , Shay Soker , Anthony Atala , Aleksander Skardal
- Applicant: Yuanyuan Zhang , Shay Soker , Anthony Atala , Aleksander Skardal
- Applicant Address: US NC Winston-Salem
- Assignee: Wake Forest University Health Sciences
- Current Assignee: Wake Forest University Health Sciences
- Current Assignee Address: US NC Winston-Salem
- Agency: Saul Ewing Arnstein & Lehr LLP
- Agent Kathryn Doyle
- International Application: PCT/US2011/059349 WO 20111104
- International Announcement: WO2012/064606 WO 20120518
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C12N5/071
Abstract:
The present invention relates to compositions and methods for mimicking an in vivo environment for culturing cells in vitro. The in vivo mimicking environment is based on the generation of a tissue-specific extracellular matrix wherein the matrix provides a substrate for which the cultured cell originated from. The tissue-specific extracellular matrix can further comprise a component of a whole tissue-specific homogenate.
Public/Granted literature
- US20130288375A1 Tissue-Specific Extracellular Matrix With or Without Tissue Protein Components for Cell Culture Public/Granted day:2013-10-31
Information query
