Invention Grant
- Patent Title: Differentiation of human iPS cells to human alveolar type II via definitive endoderm
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Application No.: US14055573Application Date: 2013-10-16
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Publication No.: US09938503B2Publication Date: 2018-04-10
- Inventor: Laura E. Niklason , Mahboobe Ghaedi
- Applicant: YALE UNIVERSITY
- Applicant Address: US CT New Haven
- Assignee: Yale University
- Current Assignee: Yale University
- Current Assignee Address: US CT New Haven
- Agency: Saul Ewing Arnstein & Lehr LLP
- Agent Kathryn Doyle
- Main IPC: C12N5/071
- IPC: C12N5/071 ; A61K35/42
Abstract:
The present invention relates to compositions and methods for generating populations of tissue precursor cells from pluripotent cells, and preferably induction of stem cells into definitive endoderm to generate anterior foregut endoderm from pluripotent cells. The anterior foregut endoderm cells can then be differentiated into an alveolar epithelial type II cell.
Public/Granted literature
- US20140105870A1 Differentiation of Human IPS Cells to Human Alveolar Type II Via Definitive Endoderm Public/Granted day:2014-04-17
Information query
