CRISPR/CAS-related methods and compositions for treating leber's congenital amaurosis 10 (LCA10)

Invention Grant

US09938521B2 CRISPR/CAS-related methods and compositions for treating leber's congenital amaurosis 10 (LCA10) 有权

Patent Title: CRISPR/CAS-related methods and compositions for treating leber's congenital amaurosis 10 (LCA10)
Application No.: US14644181

Application Date: 2015-03-10
Publication No.: US09938521B2

Publication Date: 2018-04-10
Inventor: Morgan L. Maeder , David A. Bumcrot , Shen Shen
Applicant: EDITAS MEDICINE, INC.
Applicant Address: US MA Cambridge
Assignee: EDITAS MEDICINE, INC.
Current Assignee: EDITAS MEDICINE, INC.
Current Assignee Address: US MA Cambridge
Agency: Perkins Coie LLP
Agent Patrick D. Morris
Main IPC: C12N15/10
IPC: C12N15/10 ; A61K48/00 ; C12N15/11 ; C12N7/00 ; C12N9/22 ; C12N15/113 ; C12N15/86

Abstract:

CRISPR/CAS-related compositions and methods for treatment of Leber's Congenital Amaurosis 10 (LCA10) are disclosed.

Public/Granted literature

Information query

Espacenet

IPC分类:

C	化学；冶金
C12	生物化学；啤酒；烈性酒；果汁酒；醋；微生物学；酶学；突变或遗传工程
C12N	微生物或酶；其组合物；繁殖、保藏或维持微生物；变异或遗传工程；培养基（微生物学的试验介质入C12Q1/00）。
C12N15/00	突变或遗传工程；遗传工程涉及的DNA或RNA，载体（如质粒）或其分离、制备或纯化；所使用的宿主（突变体或遗传工程制备的微生物本身入C12N1/00、C12N5/00、C12N7/00；新的植物入A01H；用组织培养技术再生植物入A01H4/00；新的动物入A01K67/00；含有插入活体细胞的遗传物质以治疗遗传疾病的药剂的应用，基因疗法入A61K48/00，一般肽入C07K）
C12N15/09	.DNA重组技术
C12N15/10	..分离、制备或纯化DNA或RNA的方法（DNA或RNA的化学制备入C07H21/00；自微生物中或用酶制备非结构多核苷酸入C12P19/34）