Invention Grant
- Patent Title: High throughput sequencing of end regions of long linear DNAs
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Application No.: US14865234Application Date: 2015-09-25
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Publication No.: US09938522B2Publication Date: 2018-04-10
- Inventor: Shihong Li , Narisra Jongkam , Ruqin Kou , Hairong Duan , Zhenzhen Zhou , Shifang Zhang
- Applicant: Genewiz, Inc.
- Applicant Address: US NJ South Plainfield
- Assignee: GENEWIZ, INC.
- Current Assignee: GENEWIZ, INC.
- Current Assignee Address: US NJ South Plainfield
- Agency: Scully Scott Murphy & Presser
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12P19/34 ; C12N15/10
Abstract:
This invention relates to linking, amplifying and sequencing of two ends of long linear DNAs. In particular, this invention provides methods for pairing and sequencing VH and VL genes that encode two parts of one immunoglobulin. The method of the present invention can be applied to rapid antibody discovery and engineering.
Public/Granted literature
- US20160090590A1 HIGH THROUGHPUT SEQUENCING OF END REGIONS OF LONG LINEAR DNAs Public/Granted day:2016-03-31
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