Invention Grant
- Patent Title: Methods and pharmaceutical compositions for treating human immunodeficiency virus type 1 (HIV-1) infections
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Application No.: US15534321Application Date: 2015-12-10
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Publication No.: US09938528B2Publication Date: 2018-04-10
- Inventor: Guido Kroemer , Jean-Luc Perfettini , Marie-Lise Gougeon , Awatef Allouch , Mauro Piacentini
- Applicant: INSERM (Institut National de la Sante et de la Recherche Medicale) , Universite Paris-Sud , Institut Gustave Roussy , Universite Paris Descartes , Universite Pierre et Marie Curie (Paris 6) , Institut Pasteur , Istituto Nazionale per Le Malattie Infettive IRCCS Lazzaro Spallanzani , Assistance Publique-Hopitaux de Paris (APHP)
- Applicant Address: FR Paris FR Orsay FR Villejuif FR Paris FR Paris FR Paris IT Rome FR Paris
- Assignee: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM),UNIVERSITE PARIS-SUD,INSTITUT GUSTAVE ROUSSY,UNIVERSITE PARIS DECARTES,UNIVERSITE PIERRE ET MARIE CURIE,INSTITUT PASTEUR,INSTITUTO NAZIONALE PER LE MALATTIE INFETTIE IRCCS LAZZARO SPALLANZANI,ASSISTANCE PUBLIQUE HOPITAUX DE PARIS (APHP)
- Current Assignee: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM),UNIVERSITE PARIS-SUD,INSTITUT GUSTAVE ROUSSY,UNIVERSITE PARIS DECARTES,UNIVERSITE PIERRE ET MARIE CURIE,INSTITUT PASTEUR,INSTITUTO NAZIONALE PER LE MALATTIE INFETTIE IRCCS LAZZARO SPALLANZANI,ASSISTANCE PUBLIQUE HOPITAUX DE PARIS (APHP)
- Current Assignee Address: FR Paris FR Orsay FR Villejuif FR Paris FR Paris FR Paris IT Rome FR Paris
- Agency: Whitham, Curtis & Cook
- Priority: EP14307001 20141211
- International Application: PCT/EP2015/079310 WO 20151210
- International Announcement: WO2016/092041 WO 20160616
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C12N15/113 ; A61K45/06 ; A61K31/683 ; A61K31/5517 ; A61K31/165 ; A61K31/395 ; A61K31/17 ; A61K31/713 ; C12Q1/18

Abstract:
The present invention provides methods and pharmaceutical compositions for treating human immunodeficiency virus type 1 (HIV-1) infections. In particular, the present invention relates to a method for treating HIV-1 infection in a subject in need thereof comprising administering the subject with a therapeutically effective amount of an inhibitor of SGT1 activity or expression.
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