Invention Grant
- Patent Title: Methods for identifying modulators of Ras using nonlinear techniques
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Application No.: US14376613Application Date: 2012-11-02
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Publication No.: US09938560B2Publication Date: 2018-04-10
- Inventor: Joshua S. Salafsky , Ryan P. McGuinness
- Applicant: Biodesy, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Biodesy, Inc.
- Current Assignee: Biodesy, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Wilson Sonsini Goodrich & Rosati
- International Application: PCT/US2012/063286 WO 20121102
- International Announcement: WO2013/115867 WO 20130808
- Main IPC: C12Q1/34
- IPC: C12Q1/34 ; C07K14/82 ; C12Q1/42
Abstract:
Provided herein are compositions and methods for identifying and detecting modulators of Ras protein conformational states through the use of second harmonic generation (SHG) technology. Also provided herein are methods for detecting a conformational changes in the three dimensional structure of a protein bound to a supported lipid bilayer.
Public/Granted literature
- US20150051110A1 METHODS FOR IDENTIFYING MODULATORS OF RAS USING NONLINEAR TECHNIQUES Public/Granted day:2015-02-19
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