An LED illumination device capable of disassembling, assembling and combining modules and slidably adjusting locations of modules, and corresponding control method for LED modules. The illumination device comprises a housing and LED modules. At least one slideway is arranged in the housing. The LED modules are removably arranged in any location in any slideways, the device can quickly realize multiple illumination solutions of changing luminance and illuminant colors, so that the LED illumination device can be conveniently applied to various operating environments and can be freely converted in the solutions of applying to various operating environments. Moreover, the control method for the LED modules can implement flexible and varied control on each LED module via an electrode orbit so that the LED illumination device can realize multiple preset illumination solutions, thereby achieving a landscape illumination effect.