Embodiments relate to a virtualized storage environment with one or more virtual machines operating on a host and sharing host resources. Each virtual machine has a virtual disk in communication with a persistent storage device. The virtual machine(s) may be misaligned with the persistent storage device so that a virtual block address does not correspond with a persistent storage block address. A relationship between the virtual disk(s) and the persistent storage device is established, and more specifically, an alignment delta between the devices is established. The delta is employed to translate the virtual address to the persistent address so that the virtual and persistent storage blocks are aligned to satisfy a read or write operation.