The present invention discloses a method for determining an interleaver, including: determining an interleaver identifier according to a binding parameter and a preset association relationship between the interleaver identifier and the binding parameter; performing interleaving processing on to-be-sent data by using an interleaver corresponding to the interleaver identifier; and performing de-interleaving processing on received data by using the interleaver corresponding to the interleaver identifier. An embodiment of the present invention further provides a corresponding device. According to technical solutions of the present invention, during data transmission, a UE and an eNodeB can accurately learn an interleaver that is used by the other party, thereby de-interleaving data correctly.