Invention Grant
- Patent Title: In vitro method for identifying compounds of the Nav 1.9 sodium channel intended for the treatment of an inflammatory skin disease
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Application No.: US14757529Application Date: 2014-06-27
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Publication No.: US09944699B2Publication Date: 2018-04-17
- Inventor: Marcel Crest , Patrick Delmas , Aurélie Lonigro-Rame , Nancy Osorio
- Applicant: GALDERMA RESEARCH & DEVELOPMENT , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , UNIVERSITE D'AIX-MARSEILLE
- Applicant Address: FR Biot
- Assignee: GALDERMA RESEARCH & DEVELOPMENT
- Current Assignee: GALDERMA RESEARCH & DEVELOPMENT
- Current Assignee Address: FR Biot
- Agency: Dentons US LLP
- Priority: FR1356349 20130628
- International Application: PCT/FR2014/051642 WO 20140627
- International Announcement: WO2014/207401 WO 20141231
- Main IPC: C07K16/28
- IPC: C07K16/28 ; C12N15/113 ; G01N33/50 ; A61K39/00
Abstract:
The use of a modulator of the Nav 1.9 sodium channel is described for treating an inflammatory skin disease. Also described, is a pharmaceutical composition including a modulator of the Nav 1.9 sodium channel, and in vitro diagnostic methods based on the detection or quantification of Nav 1.9.
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