Invention Grant
- Patent Title: Genetically encoded calcium indicators and methods of use
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Application No.: US15342295Application Date: 2016-11-03
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Publication No.: US09945844B2Publication Date: 2018-04-17
- Inventor: Loren Looger , Karel Svoboda , Douglas Kim , Rex Kerr
- Applicant: Howard Hughes Medical Institute
- Applicant Address: US MD Chevy Chase
- Assignee: Howard Hughes Medical Institute
- Current Assignee: Howard Hughes Medical Institute
- Current Assignee Address: US MD Chevy Chase
- Agency: Fish & Richardson P.C.
- Main IPC: C07K14/47
- IPC: C07K14/47 ; G01N33/50 ; C07K14/00
Abstract:
Genetically encoded calcium indicator (GECI) polypeptides and the nucleic acid molecules encoding such polypeptides are provided. In addition, methods of using such nucleic acids and polypeptides in methods of screening for agonists or antagonists of G-protein coupled receptor (GPCR) or ion channels and methods of monitoring neural activity also are provided.
Public/Granted literature
- US20170292943A1 GENETICALLY ENCODED CALCIUM INDICATORS AND METHODS OF USE Public/Granted day:2017-10-12
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