A roof rack system has a clamping system comprised of handles, a ratcheting mechanism, and a pair of jaws. The jaws provide a universal clamping system that will attach to most roof rack cross bars with an easy-on/easy-off, quick-release actuator, such as a ratcheting mechanism or lever system, that will integrate with a wide variety of accessories. The ratcheting mechanism provides compression of the attached accessory, securing it to a roof rack cross bar. This system is easier to use, more versatile, and less expensive than conventional roof rack accessory systems.