Invention Grant
- Patent Title: Thiazole-based inhibitors of scavenger receptor BI
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Application No.: US14436626Application Date: 2013-10-21
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Publication No.: US09951055B2Publication Date: 2018-04-24
- Inventor: Chris Dockendorff , Willmen Youngsaye , Partha Pratim Nag , Timothy A. Lewis , Sivaraman Dandapani , Benito Munoz , Patrick Faloon , Thomas Nieland , Monty Krieger , Miao Yu
- Applicant: THE BROAD INSTITUTE, INC. , MASSACHUSETTS INSTITUTE OF TECHNOLOGY
- Applicant Address: US MA Cambridge US MA Cambridge
- Assignee: Massachusetts Institute of Technology,The Broad Institute, Inc.
- Current Assignee: Massachusetts Institute of Technology,The Broad Institute, Inc.
- Current Assignee Address: US MA Cambridge US MA Cambridge
- Agency: Pepper Hamilton LLP
- Agent Thomas J. Engellenner; Reza Mollaaghababa
- International Application: PCT/US2013/065988 WO 20131021
- International Announcement: WO2014/063167 WO 20140424
- Main IPC: C07D277/44
- IPC: C07D277/44 ; C07D417/12 ; C07D417/14 ; C07D417/04 ; C07D491/048
Abstract:
This application describes compounds and methods that can inhibit Scavenger receptor class B, type I (SR-BI) activity, which compounds and methods can used, for example, to mediate high-density lipoprotein (HDL) lipid uptake and treat hepatitis C viral infections.
Public/Granted literature
- US20160060254A1 THIAZOLE-BASED INHIBITORS OF SCAVENGER RECEPTOR BI Public/Granted day:2016-03-03
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