Invention Grant
- Patent Title: Benzimidazole and imadazopyridine carboximidamide compounds
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Application No.: US15153527Application Date: 2016-05-12
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Publication No.: US09951065B2Publication Date: 2018-04-24
- Inventor: Mark J. Bartlett , Julian Andrew Codelli , Britton Kenneth Corkey , Jennifer Leigh Cosman , Kristyna Elbel , Jennifer Alissa Loyer-Drew , David Sperandio , Joshua Van Veldhuizen , Hai Yang , Suet Chung Yeung
- Applicant: Gilead Sciences, Inc.
- Applicant Address: US CA Foster City
- Assignee: Gilead Sciences, Inc.
- Current Assignee: Gilead Sciences, Inc.
- Current Assignee Address: US CA Foster City
- Main IPC: C07D235/06
- IPC: C07D235/06 ; C07D235/24 ; C07D295/125 ; C07D401/12 ; C07D471/04 ; A61K45/06 ; C07D235/08 ; A61K31/4184 ; A61K31/5377 ; A61K31/454 ; A61K31/437 ; A61K31/506 ; A61K31/497 ; A61K31/55 ; A61K31/541 ; A61K31/439 ; C07D405/12 ; C07D405/14 ; C07D471/08 ; A61K31/553 ; C07D235/30 ; C07D235/14 ; C07D401/04 ; C07D235/12 ; A61K31/444 ; A61K31/4545 ; A61K31/538 ; A61K31/5386 ; A61K31/438 ; C07D403/12 ; A61K31/4439 ; C07D413/12 ; A61K31/496 ; C07D487/04 ; A61K31/4725 ; C07D235/28 ; C07D235/16 ; C07D409/12

Abstract:
The present disclosure provides indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors of Formula I: or pharmaceutically acceptable salts thereof, in which X, L, n, m, R1, R2a, R2b, Rn, Rm, and Rt are as defined herein, as well as pharmaceutical compositions that include a compound of Formula I, or pharmaceutically acceptable salts thereof, and methods of using the same to treat conditions mediated by IDO1.
Public/Granted literature
- US20160333009A1 BENZIMIDAZOLE AND IMADAZOPYRIDINE CARBOXIMIDAMIDE COMPOUNDS Public/Granted day:2016-11-17
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