Invention Grant
- Patent Title: Immortalization of epithelial cells and methods of use
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Application No.: US15040783Application Date: 2016-02-10
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Publication No.: US09951315B2Publication Date: 2018-04-24
- Inventor: Richard Schlegel , Xuefeng Liu
- Applicant: Georgetown University
- Applicant Address: US DC Washington
- Assignee: Georgetown University
- Current Assignee: Georgetown University
- Current Assignee Address: US DC Washington
- Agency: Morgan, Lewis & Bockius LLP
- Main IPC: C12N5/071
- IPC: C12N5/071 ; C12Q1/68 ; G01N33/50

Abstract:
The present invention is directed towards methods of culturing non-keratinocyte epithelial cells, with the methods comprising culturing non-keratinocyte epithelial cells in the presence of feeder cells and a calcium-containing medium while inhibiting the activity of Rho kinase (ROCK) in the feeder cell, the non-keratinocyte epithelial cells or both during culturing.
Public/Granted literature
- US20160289644A1 Immortalization of Epithelial Cells and Methods of Use Public/Granted day:2016-10-06
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