Invention Grant
- Patent Title: Adenoviral vector encoding human atonal homolog-1 (HATH1)
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Application No.: US14879318Application Date: 2015-10-09
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Publication No.: US09951351B2Publication Date: 2018-04-24
- Inventor: Douglas E. Brough , Damodar R. Ettyreddy
- Applicant: GenVec, Inc.
- Applicant Address: US MD Gaithersburg
- Assignee: GenVec, Inc.
- Current Assignee: GenVec, Inc.
- Current Assignee Address: US MD Gaithersburg
- Agency: Leydig, Voit & Mayer, Ltd.
- Main IPC: C12N15/861
- IPC: C12N15/861 ; C12N15/86 ; A61K38/16 ; A61K48/00
Abstract:
The invention is directed to a replication-deficient adenoviral vector comprising a nucleic acid sequence encoding a human atonal homolog-1 (Hath1) protein operably linked to a human glial fibrillary acidic protein (GFAP) promoter. The invention also is directed to a composition and method utilizing the adenoviral vector to generate sensory cells in the inner ear of a human.
Public/Granted literature
- US20160102320A1 ADENOVIRAL VECTOR ENCODING HUMAN ATONAL HOMOLOG-1 (HATH1) Public/Granted day:2016-04-14
Information query
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