Invention Grant
- Patent Title: Isothermal DNA amplification
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Application No.: US13330745Application Date: 2011-12-20
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Publication No.: US09951379B2Publication Date: 2018-04-24
- Inventor: John Richard Nelson , Robert Scott Duthie , Carl Williams Fuller , Gregory Andrew Grossmann , Anuradha Sekher
- Applicant: John Richard Nelson , Robert Scott Duthie , Carl Williams Fuller , Gregory Andrew Grossmann , Anuradha Sekher
- Applicant Address: US NY Schenectady
- Assignee: GENERAL ELECTRIC COMPANY
- Current Assignee: GENERAL ELECTRIC COMPANY
- Current Assignee Address: US NY Schenectady
- Agent Pabitra K. Chakrabarti
- Main IPC: C12Q1/68
- IPC: C12Q1/68

Abstract:
Provided herein are nucleic acid synthesis methods and agents that employ an endonuclease for example, endonuclease V, to introduce a nick into a target DNA including one or more inosine, and uses a DNA polymerase to generate amplicons of the target DNA.
Public/Granted literature
- US20120196330A1 ISOTHERMAL DNA AMPLIFICATION Public/Granted day:2012-08-02
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