An interface system that allows for tactile manipulation of a touch screen for people with disabilities and which provides appropriate tactile marking for the action they wish to carry out and that may afford a sensation that a button is being pressed to a user, is provided. The system includes a touch screen and a tactile button assembly that extends over at least a portion of the touch screen. The tactile button assembly includes tactile buttons with tactile indicia that can be felt by a user. The tactile buttons are arranged with respect to the touch screen so that when a tactile button is pressed by a user, a contact end of the tactile button contacts a button on the touch screen to perform a predetermined task associated with pressing such button on the touch screen.