The system and method may measure and monitor physiological changes in a body. In some embodiments, the system and method may measure the impedance at a site in the body. In some embodiments, the system and method identify, quantify, and localize leaks from a site following surgery, measure cardiac contractility, or lung compliance. In an embodiment, the system includes a measuring device with one or more sensors embedded in a porous matrix. Changes in the electrical properties of one or more sensors may be used to determine the presence of leaks from a site following surgery, measure cardiac contractility, or lung compliance, depending on the position of the device.